Vaccines including antigen from four strains of influenza virus
作者： Theodore F. Tsai
DOI:
关键词:
摘要: Vaccines of the invention include at least four influenza virus strains. In some embodiments, vaccines are produced in cell culture rather than eggs. an adjuvant. not split or whole virion vaccines, but live purified glycoprotein vaccines. contain substantially same mass hemagglutinin (HA) for each strains will two A and B ('A-A-B-B'). other three one strain ('A-A-A-B').
lens.org参考文章(124)
Charles E. Weeks, John F. Gerster, 2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines ,(1991)
Robert G. Webster, Nicolai V. Kaverin, Influenza virus replicated in mammalian cell culture and vaccine production ,(1997)
Richard Franck, Guangwu Chen, Moriya Tsuji, Novel synthetic c-glycolipids, their synthesis and use to treat infections, cancer and autoimmune diseases ,(2005)
Jonathan A. McCullers, George C. Wang, Shiqin He, Robert G. Webster, Reassortment and Insertion-Deletion Are Strategies for the Evolution of Influenza B Viruses in Nature Journal of Virology. ,vol. 73, pp. 7343- 7348 ,(1999) , 10.1128/JVI.73.9.7343-7348.1999
Volker Dr. Sandig, Ingo Dr. Jordan, Immortalized avian cell lines for virus production ,(2004)
Jens Peter Gregersen, Decreasing potential iatrogenic risks associated with influenza vaccines ,(2005)
Craig T. Przysiecki, Paolo Ingallinella, Xiaoping Liang, John W. Shiver, Roxana Ionescu, Li Shi, Victor M. Garsky, Elisabetta Bianchi, Antonello Pessi, Influenza virus vaccine ,(2004)
X. Xu, J. Shaw, C.B. Smith, N.J. Cox, A.I. Klimov, Multiple lineages co-circulation and genetic reassortment of the neuraminidase and hemagglutinin genes within influenza viruses of the same type/subtype International Congress Series. ,vol. 1219, pp. 383- 387 ,(2001) , 10.1016/S0531-5131(01)00348-X
I.G. Barr, N. Komadina, A. Hurt, R. Shaw, C. Durrant, P. Iannello, C. Tomasov, H. Sjogren, A.W. Hampson, Reassortants in recent human influenza A and B isolates from South East Asia and Oceania. Virus Research. ,vol. 98, pp. 35- 44 ,(2003) , 10.1016/J.VIRUSRES.2003.08.011
Th ME Govaert, MJW Sprenger, GJ Dinant, K Aretz, N Masurel, JA Knottnerus, None, Immune response to influenza vaccination of elderly people. A randomized double-blind placebo-controlled trial Vaccine. ,vol. 12, pp. 1185- 1189 ,(1994) , 10.1016/0264-410X(94)90241-0