Evaluating the relevance of seasonal differentiation of human health intake fractions in life cycle assessment

摘要: The intake fraction (iF) is the of an emitted mass chemical that ultimately taken in by entire population, and it used as indicator human health potential impacts related to environmental persistence bioaccumulation food chain. In screening applications, iF can be predicted using multimedia multipathway fate exposure models. One sources uncertainty natural seasonal variability input parameters models, i.e., physicochemical properties pollutant landscape parameters. objective this article determine relevance including differentiation when assessing iFs life cycle assessment. This was done calculating comparing with each other at 25° C, for both Canadian global contexts. Two models based on IMPACT 2002 predictive tool, 2 context USEtox consensus model were developed calculate summer winter iFs. Emissions into air water a set 35 representative organic chemicals considered. Partition coefficients conditions calculated integration van't Hoff equation. First-order degradation rate constants assuming constant doubles 10° C increase temperature. For emissions, results indicated emissions could up 1 orders magnitude higher than or 25° C. showed were, general, closer outliers within order Results also lesser importance context. Because ranking between maintained, concluded not relevant comparative However, difference might significant toxicity versus impact categories contributing damages. Integr Environ Assess Manag 2012; 8: 749–759. © 2012 SETAC