Circadian disruption of ICU patients: A review of pathways, expression, and interventions

摘要: Intensive care unit patients typically exhibit pathologic wakefulness, poor quality of daytime sleep, nocturnal sleep fragmentation, and patterns that feature the absence slow wave rapid eye movement. This article offers a review existing literature examining circadian desynchronization in critically ill patients, highlighting contributing factors identified by scholars, abnormalities observed these patients. It discusses potential implications for clinical practice suggests avenues future research. Elucidating role rhythms management critical illness can guide chronotherapeutic approaches optimize patient outcomes.