Morphological development of microglia in the postnatal rat brain. A quantitative study.
作者： Dariusz Orłowski , Zbigniew Sołtys , Krzysztof Janeczko
DOI: 10.1016/J.IJDEVNEU.2003.09.001
关键词:
摘要: Morphological transformation of lectin-positive microglia/macrophages in the developing rat cerebral hemisphere was analysed using quantitative methods. During first postnatal month, cells showed increases their size and fractal dimension accompanied by a simultaneous decrease solidity. Regional variations dynamics process indicated existence spatio-temporal developmental gradients within wall which might correspond with regional patterns neuronal differentiation. Results present study prove that methods can be source reliable data replacing subjective cell typologies.
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