Effects of neoadjuvant intraperitoneal/systemic chemotherapy (bidirectional chemotherapy) for the treatment of patients with peritoneal metastasis from gastric cancer.

作者: Yutaka Yonemura , Ayman Elnemr , Yoshio Endou , Haruaki Ishibashi , Akiyoshi Mizumoto

DOI: 10.1155/2012/148420

关键词:

摘要: Novel multidisciplinary treatment combined with neoadjuvant intraperitoneal-systemic chemotherapy protocol (NIPS) and peritonectomy was developed. Ninety-six patients were enrolled. Peritoneal wash cytology performed before after NIPS through a port system. Patients treated 60 mg/m2 of oral S-1 for 21 days, followed by 1-week rest. On days 1, 8, 15, 30 mg/m2 Taxotere cisplatin 500 mL saline introduced the port. is done 2 cycles surgery. Three weeks NIPS, 82 eligible to intend cytoreductive surgery (CRS) gastrectomy

参考文章(22)
Eelco Bree, Dimitris D. Tsiftsis, Experimental and Pharmacokinetic Studies in Intraperitoneal Chemotherapy: From Laboratory Bench to Bedside Recent results in cancer research. ,vol. 169, pp. 53- 73 ,(2007) , 10.1007/978-3-540-30760-0_5
J. Gordon McVie, Glenn S. Baldew, Peter H. A. Mutsaers, Peter W. de Graaf, Gerrit Los, Wim J. F. van der Vijgh, Direct Diffusion of cis-Diamminedichloroplatinum(II) in Intraperitoneal Rat Tumors after Intraperitonal Chemotherapy: A Comparison with Systemic Chemotherapy Cancer Research. ,vol. 49, pp. 3380- 3384 ,(1989)
P Preusser, H Wilke, W Achterrath, U Fink, L Lenaz, A Heinicke, J Meyer, H J Meyer, H Buente, Phase II study with the combination etoposide, doxorubicin, and cisplatin in advanced measurable gastric cancer. Journal of Clinical Oncology. ,vol. 7, pp. 1310- 1317 ,(1989) , 10.1200/JCO.1989.7.9.1310
M. A. Baron, Structure of the intestinal peritoneum in man American Journal of Anatomy. ,vol. 69, pp. 439- 497 ,(1941) , 10.1002/AJA.1000690305
Mario Valle, Alfredo Garofalo, Laparoscopic staging of peritoneal surface malignancies Ejso. ,vol. 32, pp. 625- 627 ,(2006) , 10.1016/J.EJSO.2006.03.015
Hideo Baba, Manabu Yamamoto, Kazuya Endo, Yasuharu Ikeda, Yasushi Toh, Shunji Kohnoe, Takeshi Okamura, None, Clinical efficacy of S-1 combined with cisplatin for advanced gastric cancer Gastric Cancer. ,vol. 6, pp. 45- 49 ,(2003) , 10.1007/S10120-003-0222-Y
M Inokuchi, T Yamashita, H Yamada, K Kojima, W Ichikawa, Z Nihei, T Kawano, K Sugihara, Phase I/II study of S-1 combined with irinotecan for metastatic advanced gastric cancer. British Journal of Cancer. ,vol. 94, pp. 1130- 1135 ,(2006) , 10.1038/SJ.BJC.6603072
Ju-Li Koh, Tristan D. Yan, Derek Glenn, David L. Morris, Evaluation of preoperative computed tomography in estimating peritoneal cancer index in colorectal peritoneal carcinomatosis. Annals of Surgical Oncology. ,vol. 16, pp. 327- 333 ,(2009) , 10.1245/S10434-008-0234-2
Babak Sadeghi, Catherine Arvieux, Olivier Glehen, Annie C Beaujard, Michel Rivoire, Jacques Baulieux, Eric Fontaumard, Alain Brachet, Jean L Caillot, Jean L Faure, Jack Porcheron, Jean L Peix, Yves François, Jacques Vignal, François N Gilly, None, Peritoneal carcinomatosis from non-gynecologic malignancies: results of the EVOCAPE 1 multicentric prospective study. Cancer. ,vol. 88, pp. 358- 363 ,(2000) , 10.1002/(SICI)1097-0142(20000115)88:2<358::AID-CNCR16>3.0.CO;2-O