Subgenomic messenger RNAs: Mastering regulation of (+)-strand RNA virus life cycle

摘要: Many (+)-strand RNA viruses use subgenomic (SG) RNAs as messengers for protein expression, or to regulate their viral life cycle. Three different mechanisms have been described the synthesis of SG RNAs. The first mechanism involves internal initiation on a (-)-strand template and requires an SGP promoter. second makes prematurely terminated which is used make RNA. third uses discontinuous while making templates. Most are translated into structural proteins related pathogenesis: however other transition between translation replication, function riboregulators replication translation, support RNA-RNA recombination. In this review we discuss these functions how they influence