摘要: Pain is commonly categorized into two diverse groups: acute pain, characterized by early onset and last for a very short time; while chronic prolonged pain least 3 months’ duration. Timely immediate management of critical in reducing its aggravation to pain. There has been successful application nano-technology, nano-medicine the treatment both clinical experimental studies like fabrication nano-formulated liposomes deliver drugs therapy, formulation non- steroidal anti-inflammatory (NSAIDs). However safety issues related with NSAIDs have impelled design new drug formulations that reduces side effects sustain efficacy. This review will give concise summary on available designed management.