Distribution of PCBs, Their Hydroxylated Metabolites, and Other Phenolic Contaminants in Human Serum from Two European Countries

作者: Alin C. Dirtu , Veerle L. B. Jaspers , Roberta Cernat , Hugo Neels , Adrian Covaci

DOI: 10.1021/ES902149B

关键词:

摘要: Human exposure to mixtures of polychlorinated biphenyls (PCBs) may result in the formation different profiles hydroxylated PCBs (HO-PCBs), as a consequence exposures or dissimilar metabolism parent compounds. Therefore, we investigated levels and HO-PCBs human serum samples collected from two European countries with degrees pollution. There was no significant difference between sum measured each set samples, median concentration 3100 pg/mL for Romanian (n = 53) 3380 Belgian 22). However, concentrations recorded were almost double (310 pg/mL) compared (175 samples. The detection frequency also significantly higher main contributors 4HO-CB107 > 4HO-CB146 4HO-CB187 (76% HO-PCBs) 4...

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