Arsenolipids in oil from blue whiting Micromesistius poutassou – evidence for arsenic-containing esters
作者： Mojtaba S. Taleshi , Georg Raber , John S. Edmonds , Kenneth B. Jensen , Kevin A. Francesconi
DOI: 10.1038/SREP07492
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摘要: Arsenic-containing lipids in the oil from blue whiting fish (Micromesistius poutassou) were separated into three broad polarity groups and investigated by HPLC mass spectrometry. A total of 11 arsenolipids including 4 new compounds identified. The polar lipid fraction constituting 24% arsenolipid content (which totalled 2.16 μg As/g) contained four known dimethylarsinoyl fatty acids hydrocarbons. less (ca 30% arsenolipids) hydrocarbons with chain lengths 22–30 carbons, addition to more complex arsenicals that hydrolysed suggesting they conjugated carboxylic acids, presumably esters. rest lipid-soluble arsenic 45% total) remained non-polar together bulk lipids, a mixture precluded identification small amounts arsenolipids.
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sci-hub.se 参考文章(20)
Kenneth O Amayo, Andrea Raab, Eva M Krupp, Jörg Feldmann, Identification of arsenolipids and their degradation products in cod-liver oil. Talanta. ,vol. 118, pp. 217- 223 ,(2014) , 10.1016/J.TALANTA.2013.09.056
Veronika Sele, Jens J. Sloth, Bjarte Holmelid, Stig Valdersnes, Kasper Skov, Heidi Amlund, Arsenic-containing fatty acids and hydrocarbons in marine oils – determination using reversed-phase HPLC–ICP-MS and HPLC–qTOF-MS Talanta. ,vol. 121, pp. 89- 96 ,(2014) , 10.1016/J.TALANTA.2013.12.049
S�ren N. Pedersen, Kevin A. Francesconi, Liquid chromatography electrospray mass spectrometry with variable fragmentor voltages gives simultaneous elemental and molecular detection of arsenic compounds. Rapid Communications in Mass Spectrometry. ,vol. 14, pp. 641- 645 ,(2000) , 10.1002/(SICI)1097-0231(20000430)14:8<641::AID-RCM923>3.0.CO;2-V
Veronika Sele, Heidi Amlund, Marc H. G. Berntssen, Jannicke A. Berntsen, Kasper Skov, Jens J. Sloth, Detection of arsenic-containing hydrocarbons in a range of commercial fish oils by GC-ICPMS analysis. Analytical and Bioanalytical Chemistry. ,vol. 405, pp. 5179- 5190 ,(2013) , 10.1007/S00216-013-6925-Y
T. J. Erb, P. Kiefer, B. Hattendorf, D. Gunther, J. A. Vorholt, GFAJ-1 Is an Arsenate-Resistant, Phosphate-Dependent Organism Science. ,vol. 337, pp. 467- 470 ,(2012) , 10.1126/SCIENCE.1218455
Ramon Segura, Preparation of fatty acid methyl esters by direct transesterification of lipids with aluminium chloride-methanol. Journal of Chromatography A. ,vol. 441, pp. 99- 113 ,(1988) , 10.1016/S0021-9673(01)84658-6
Uriel Arroyo-Abad, Susanne Lischka, Christian Piechotta, Jürgen Mattusch, Thorsten Reemtsma, Determination and identification of hydrophilic and hydrophobic arsenic species in methanol extract of fresh cod liver by RP-HPLC with simultaneous ICP-MS and ESI-Q-TOF-MS detection. Food Chemistry. ,vol. 141, pp. 3093- 3102 ,(2013) , 10.1016/J.FOODCHEM.2013.05.152
Kenneth O. Amayo, Andrea Raab, Eva M. Krupp, Talke Marschall, Michael Horsfall, Jörg Feldmann, Arsenolipids show different profiles in muscle tissues of four commercial fish species. Journal of Trace Elements in Medicine and Biology. ,vol. 28, pp. 131- 137 ,(2014) , 10.1016/J.JTEMB.2013.11.004
Kenneth O. Amayo, Andrea Raab, Eva M. Krupp, Helga Gunnlaugsdottir, Jörg Feldmann, Novel identification of arsenolipids using chemical derivatizations in conjunction with RP-HPLC-ICPMS/ESMS. Analytical Chemistry. ,vol. 85, pp. 9321- 9327 ,(2013) , 10.1021/AC4020935
Pedro Traar, Alice Rumpler, Tobias Madl, Gerald Saischek, Kevin A. Francesconi, Synthesis of Naturally Occurring Arsenic-Containing Carbohydrates Australian Journal of Chemistry. ,vol. 62, pp. 538- 545 ,(2009) , 10.1071/CH08461