Dendritic cells and tumor microenvironment: a dangerous liaison.
作者： Ingo Fricke , Dmitry I. Gabrilovich
DOI: 10.1080/08820130600803429
关键词:
摘要: The fact that the immune response to cancer is compromised has been convincingly demonstrated in murine tumor models as well patients. unresponsiveness of host system one major mechanisms escape an important factor limits success immunotherapy. Inadequate function professional antigen presenting cells dendritic (DC) elements anti-tumor response. Despite substantial progress recent years, mechanism inadequate DC still remains unclear. microenvironment emerged component contributing malfunction. In this review we will discuss potential role dysfunction.
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