Multiple primary tumors including bilateral breast cancers in a man with Klinefelter's syndrome
作者： Geoffrey M. Coley , Richard D. Otis , William E. Clark
DOI: 10.1002/1097-0142(197106)27:6<1476::AID-CNCR2820270630>3.0.CO;2-T
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摘要: A 50-year-old man with Klinefelter's syndrome developed 6 histologically distinct tumors in sequence; five were considered to be malignant neoplasms. Others have reported an association between this and the development of neoplasms, especially cancer breast. The hormonal genetic factors characteristic patients may important genesis cancer.
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