Bone loss in adults receiving alternate day glucocorticoid therapy

作者: Oscar S. Gluck , William A. Murphy , Theodore J. Hahn , Bevra Hahn

DOI: 10.1002/ART.1780240705

关键词:

摘要: Bone mineral content was measured by photon absorption densitometry in 25 patients with rheumatic diseases receiving glucocorticoids on an alternate day treatment schedule, and age-, sex-, race-matched daily steroid therapy. Mean values for cortical (diaphyseal) mass, trabecular (metaphyseal) the cortical/trabecular mass ratios were not different two groups. Steroid-induced osteopenia, defined as elevated ratio of to occurred both therapeutic regimens (8 day; 11 daily). Therefore, bone loss demonstrable individuals regimens. Serum levels calcium, ionized alkaline phosphatase, parathyroid hormone similar

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