Inhibitory Action of Ruthenium Red on Neuromuscular Transmission

摘要: Abstract The effect of Ruthenium Red on synaptic transmission was examined at isolated junctions the frog, by conventional methods for stimulation and intracellular recording. (2.5-10.0 μM) reduces potential to subthreshold levels. An analysis this phenomenon shows that main action is presynaptic nerve terminal where it decreases number quanta transmitter liberated impulse. It has following additional effects: a reduction in amplitude spontaneous miniature end plate potentials; an increase their frequency; delayed release after Some these results are discussed terms known inhibitory calcium transport across mitochondrial membranes.