Aptamer-modified magnetic nano material and application thereof in separating ochratoxin A

摘要: The invention provides an aptamer-magnetic nanoparticle compound, which comprises inner nuclear layer formed by paramagnetic Fe3O4 magnetic nanoparticles, a silanization and aptamer modification located at the outer side of layer, so that compound not only has characteristic being quickly separated from complex sample solution under externally applied field, but also carrying out specificity recognition capture on detected substance using aptamer. Therefore, can be effectively provided invention, selectivity is good, separation efficiency high. Data shows recovery rate reach up to 80-92%. Furthermore, gathered then detection again, thereby capable improving accuracy.