Apoptosis (Programmed Cell Death) and the Resolution of Acute Inflammation

摘要: Biology, for the clinician, has classically encompassed study of life and growth cells organisms; death been perceived as a pathologic process to be prevented. But over past few years, our perception cell undergone major transformation [1]. It is now recognized that do not have an absolute unchangeable lifespan, but rather survival can change in response environmental stimuli. Moreover, moment’s reflection will confirm host normal biologic processes, controlled cellular only inevitable, critical development. During embryogenesis, formation mature organs dependent on remodeling tissues resulting, example, interdigital web spaces or canalization gastrointestinal tract. Deletion autoreactive T during immune maturation essential prevent autoimmune disease; other such blood cells, epithelial skin, tract are constantly formed shed life. The programmed called apoptosis.