Unitary Responses in Frog Olfactory Epithelium to Sterically Related Molecules at Low Concentrations
作者： Thomas V. Getchell
DOI: 10.1085/JGP.64.2.241
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摘要: Responses of receptor cells in the frog's olfactory epithelium were recorded using platinum-black metal-filled microelectrodes. Spontaneous activity varied over a wide range from 0.07 to 1.8 spikes/s. Mean interspike intervals ranged 13.7 0.5 s. Excitatory responses six sterically related compounds at low concentrations investigated. Stimuli delivered an aqueous medium. Thresholds for impulse initiation greater than 1 mM down nanomolar concentration range. different receptors same stimulus could vary by several log units. cell stimuli be within order magnitude, or as much 5 Based upon quantitative measures stimulus-evoked excitatory it appeared that some did not discriminate among molecules, whereas other clearly discriminated between which evoke similar odor sensations.
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