Infections bronchopulmonaires à Stenotrophomonas maltophilia et à Acinetobacter baumannii

作者: A. Baranzelli , F. Wallyn , S. Nseir

DOI: 10.1016/J.PNEUMO.2013.02.005

关键词:

摘要: Stenotrophomonas maltophilia and Acinetobacter baumannii are both non-fermenting ubiquitous Gram-negative bacilli. The incidence of lower respiratory tract infections related to these microorganisms is increasing, especially in intensive care units. Their capacity acquire resistance against several antimicrobials challenging for clinicians microbiologists. Despite their low virulence, pathogens responsible colonization infection patients with comorbidities, immunosuppression, critically ill patients. S. A. mainly identified nosocomial infections: ventilator-associated pneumonia, bacteremia surgical wound infection. Infections microorganism associated high mortality morbidity. Trimethoprime-sulfamethoxazole carbapenem the first line treatment respectively. However, increasing rate agents results difficulties treating pathogens. New antimicrobial further randomized studies needed improve infections. Prevention spared multidrug-resistant bacteria mandatory, including hand-hygiene, environment cleaning, limited usage large spectrum antibiotics.

参考文章(77)
Saad Nseir, Christophe Di Pompeo, Hélène Brisson, Florent Dewavrin, Stéphanie Tissier, Maimouna Diarra, Marie Boulo, Alain Durocher, Intensive care unit-acquired Stenotrophomonas maltophilia: incidence, risk factors, and outcome Critical Care. ,vol. 10, pp. 1- 9 ,(2006) , 10.1186/CC5063
H Seifert, L Dijkshoorn, P Gerner-Smidt, N Pelzer, I Tjernberg, M Vaneechoutte, Distribution of Acinetobacter species on human skin: comparison of phenotypic and genotypic identification methods. Journal of Clinical Microbiology. ,vol. 35, pp. 2819- 2825 ,(1997) , 10.1128/JCM.35.11.2819-2825.1997
Alfred E. Buxton, Roger L. Anderson, Dianne Werdegar, Ernest Atlas, Nosocomial respiratory tract infection and colonization with Acinetobacter calcoaceticus The American Journal of Medicine. ,vol. 65, pp. 507- 513 ,(1978) , 10.1016/0002-9343(78)90777-5
Isaac Talmaciu, Laurie Varlotta, Joel Mortensen, Daniel V. Schidlow, Risk factors for emergence of Stenotrophomonas maltophilia in cystic fibrosis Pediatric Pulmonology. ,vol. 30, pp. 10- 15 ,(2000) , 10.1002/1099-0496(200007)30:1<10::AID-PPUL3>3.0.CO;2-Q
M.-L. Joly-Guillou, Clinical impact and pathogenicity of Acinetobacter Clinical Microbiology and Infection. ,vol. 11, pp. 868- 873 ,(2005) , 10.1111/J.1469-0691.2005.01227.X
David Berlana, J. M. Llop, E. Fort, M. B. Badia, R. Jódar, Use of colistin in the treatment of multiple-drug-resistant gram-negative infections. American Journal of Health-system Pharmacy. ,vol. 62, pp. 39- 47 ,(2005) , 10.1093/AJHP/62.1.39
Joon Young Song, Hee Jin Cheong, Jacob Lee, Ah Kyeong Sung, Woo Joo Kim, Efficacy of monotherapy and combined antibiotic therapy for carbapenem-resistant Acinetobacter baumannii pneumonia in an immunosuppressed mouse model International Journal of Antimicrobial Agents. ,vol. 33, pp. 33- 39 ,(2009) , 10.1016/J.IJANTIMICAG.2008.07.008
J. I. Garcia Paez, F. M. Tengan, A. A. Barone, A. S. Levin, S. F. Costa, Factors associated with mortality in patients with bloodstream infection and pneumonia due to Stenotrophomonas maltophilia European Journal of Clinical Microbiology & Infectious Diseases. ,vol. 27, pp. 901- 906 ,(2008) , 10.1007/S10096-008-0518-2
Alex P. Betrosian, Frantzeska Frantzeskaki, Anna Xanthaki, George Georgiadis, High-dose ampicillin-sulbactam as an alternative treatment of late-onset VAP from multidrug-resistant Acinetobacter baumannii. Scandinavian Journal of Infectious Diseases. ,vol. 39, pp. 38- 43 ,(2007) , 10.1080/00365540600951184