Proteomic analysis of Girdin-interacting proteins in migrating new neurons in the postnatal mouse brain
作者： Haruko Ota , Takao Hikita , Tomoki Nishioka , Mami Matsumoto , Jun Ito
DOI: 10.1016/J.BBRC.2013.10.126
关键词:
摘要: Neural stem cells continuously generate new neurons in the ventricular-subventricular zone (V-SVZ) of postnatal and adult mammalian brain. New born rodent V-SVZ migrate toward olfactory bulb (OB), where they differentiate into interneurons. To reveal novel intracellular molecular mechanisms that control neuronal migration, we performed a global proteomic search for proteins interacting with Girdin, an essential protein migration. Using GST pull-down LC-MS/MS shotgun analysis, identified cytoskeletal proteins, cytoskeleton-binding signal-transduction as possible participants Our results suggest Girdin Girdin-interacting migration by regulating actin and/or microtubule dynamics.
sci-hub.se 参考文章(32)
Masato Sawada, Shi-hui Huang, Yuki Hirota, Naoko Kaneko, Kazunobu Sawamoto, Neuronal Migration in the Adult Brain Japanese journal of psychopharmacology. ,vol. 28, pp. 337- 355 ,(2011) , 10.1007/978-4-431-53933-9_14
Fiona Simpson, Sally Martin, Timothy M. Evans, Markus Kerr, David E. James, Robert G. Parton, Rohan D. Teasdale, Carol Wicking, A novel hook-related protein family and the characterization of hook-related protein 1. Traffic. ,vol. 6, pp. 442- 458 ,(2005) , 10.1111/J.1600-0854.2005.00289.X
M. Sakamoto, I. Imayoshi, T. Ohtsuka, M. Yamaguchi, K. Mori, R. Kageyama, Continuous neurogenesis in the adult forebrain is required for innate olfactory responses. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 108, pp. 8479- 8484 ,(2011) , 10.1073/PNAS.1018782108
C Lois, A Alvarez-Buylla, Long-distance neuronal migration in the adult mammalian brain Science. ,vol. 264, pp. 1145- 1148 ,(1994) , 10.1126/SCIENCE.8178174
Toshiyuki Mizui, Nobuhiko Kojima, Hiroyuki Yamazaki, Michihito Katayama, Kenji Hanamura, Tomoaki Shirao, Drebrin E is involved in the regulation of axonal growth through actin-myosin interactions Journal of Neurochemistry. ,vol. 109, pp. 611- 622 ,(2009) , 10.1111/J.1471-4159.2009.05993.X
Alexey I. Nesvizhskii, Andrew Keller, Eugene Kolker, Ruedi Aebersold, A statistical model for identifying proteins by tandem mass spectrometry. Analytical Chemistry. ,vol. 75, pp. 4646- 4658 ,(2003) , 10.1021/AC0341261
Aleksandar Jankovski, Constantino Sotelo, Subventricular zone-olfactory bulb migratory pathway in the adult mouse: cellular composition and specificity as determined by heterochronic and heterotopic transplantation. The Journal of Comparative Neurology. ,vol. 371, pp. 376- 396 ,(1996) , 10.1002/(SICI)1096-9861(19960729)371:3<376::AID-CNE3>3.0.CO;2-#
Y. Wang, N. Kaneko, N. Asai, A. Enomoto, M. Isotani-Sakakibara, T. Kato, M. Asai, Y. Murakumo, H. Ota, T. Hikita, T. Namba, K. Kuroda, K. Kaibuchi, G.-l. Ming, H. Song, K. Sawamoto, M. Takahashi, Girdin Is an Intrinsic Regulator of Neuroblast Chain Migration in the Rostral Migratory Stream of the Postnatal Brain The Journal of Neuroscience. ,vol. 31, pp. 8109- 8122 ,(2011) , 10.1523/JNEUROSCI.1130-11.2011
Maria B. Luskin, Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone Neuron. ,vol. 11, pp. 173- 189 ,(1993) , 10.1016/0896-6273(93)90281-U
D. R. Kornack, P. Rakic, The generation, migration, and differentiation of olfactory neurons in the adult primate brain Proceedings of the National Academy of Sciences of the United States of America. ,vol. 98, pp. 4752- 4757 ,(2001) , 10.1073/PNAS.081074998