Serological Studies of Normal and Leukemic Cats in a Multiple-Case Leukemia Cluster

作者: M. Essex , Susan M. Cotter , William D. Hardy

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摘要: Summary Eleven cases of lymphoblastic leukemia and four feline infectious peritonitis occurred in a private household population 35 predominantly unrelated cats over 39-month period. The study conducted on this consisted periodic physical examinations, hemograms, serological testing for virus group-specific antigens ( gs ) antibody to oncornavirus-associated cell membrane antigen (FOCMA). Serological values were compared those healthy leukemic control from the same geographical area. Leukemic had higher mean age been longer than that remained healthy. Six 9 positive FeLV (as 10 living other environments). Both cluster also low geometric titers FOCMA (0.72 0.76, respectively). This differed controls outside house all negative titer 1.66. For within house, was 4.65 5 17 antigens. difference is apparently due more frequent or recent exposure household. Relatives no likely develop become relatives cats. Cats developing appear be unable produce maintain high titer. It concluded these data support theory horizontal transmission virus.

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