作者: Ish Khanna
DOI: 10.1016/J.DRUDIS.2012.05.007
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摘要: Low productivity, rising R&D costs, dissipating proprietary products and dwindling pipelines are driving the pharmaceutical industry to unprecedented challenges scrutiny. In this article I reflect on current status of reasons for continued low productivity. An emerging 'symbiotic model innovation', that addresses underlying issues in drug failure attempts narrow gaps discovery processes, is discussed boost The emphasizes partnerships innovation deliver quality a cost-effective system. also discuss diverse options build balanced research portfolio with higher potential persistent delivery molecules.