Activation Requirements for Resting T Lymphocytes

摘要: The growth of T lymphocytes is generally believed to be under dual control (reviewed in Smith 1980). Initially, interaction specific antigen receptors on the T-cell surface with (or its presumed operational equivalent mitogenic lectin) leads expression for polypeptide hormone interleukin 2 (IL2). Following IL2 receptor expression, subsequent regulated by concentration both IL2-receptors and itself a manner similar that observed other hormones. In context such model, “activation” can defined rather narrowly as series events which are required induce responsiveness (i.e., expression).