Local Anesthetics Suppress Nerve Growth Factor-Mediated Neurite Outgrowth by Inhibition of Tyrosine Kinase Activity of TrkA

作者: Mayumi Takatori , Yoshihiro Kuroda , Munetaka Hirose

DOI: 10.1213/01.ANE.0000194334.69103.50

关键词:

摘要: Local anesthetics (LAs) suppress sympathetic sprouting, which correlates with neuropathic pain. However, the precise mechanism of suppression is unknown. Nerve growth factor (NGF) contributes to and NGF signaling starts NGF-stimulated autophosphorylation TrkA,

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