摘要: Current tumor markers are limited in their clinical utilities. They only useful for monitoring cancer patients during treatment and detecting recurrence. Because of the lack specificity sensitivity, currently used not recommended screening or diagnosis. Therefore, new being sought to improve sensitivity detection In this chapter we introduce several complement markers. These may provide improved management. Recently importance using target therapy, prognosis, early has been emphasized (1). there is a need discover circulating use these areas. Introduced that appear have addition, group also described relating signal transduction pathway, cell cycle, apoptosis, angiogenesis, adhesion. This addition largely owing recent change emphasis on Instead stressing diagnosis, recurrence, placed at detection, therapy. Note detectable blood circulation. appearance circulation associated with various stages growth regulation cells, could be correlated prognosis neoplasm, identifiable as As will shown below, involve oncoproteins mutated suppressor proteins but enzymes factors. Although yet fully verified, here should greatly