Proliferation and Differentiation of Testicular Interstitial Cells: Aspects of Leydig Cell Development in the (Pre)Pubertal and Adult Testis

作者: K. J. Teerds , M. B. Veldhuizen-Tsoerkan , F. F. G. Rommerts , D. G. Rooij , J. H. Dorrington

DOI: 10.1007/978-3-662-22189-1_3

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摘要: It has been known for several decades that the gonadotrophine luteinizing hormone (LH) and follicle-stimulating (FSH) are required normal growth differentiation of Leydig cells Sertoli cells, respectively (Greep et al. 1936; Christensen 1975). The actions these gonadotrophins on somatic testis result in establishment appropriate microenvironment seminiferous tubule is conducive to process spermatogenesis (Dorrington Armstrong 1979). One essential factors progression testosterone. gonadotrophin LH acts stimulate synthesis secretion this androgen, which subsequently as a paracrine factor within tubules (Ahmad 1973; Sharpe 1987).

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