Engineering High-Affinity T Cell Receptor/ Cytokine Fusions for Therapeutic Targeting

作者: Jennifer D. , Yiyuan Yin , Min Mo , K. Scott , David L.

DOI: 10.5772/28826

关键词:

摘要: Jennifer D. Stone1, Yiyuan Yin2, Min Mo2, K. Scott Weber3, David L. Donermeyer3, Paul M. Allen3,Roy A. Mariuzza2,4 and Kranz 1 1Department of Biochemistry, University Illinois at Urbana-Champaign, Urbana, 2Institute for Bioscience Biotechnology Research, Maryland, Rockville, 3Department Pathology Immunology, Washington School Medicine, St. Louis, 4Department Cell Biology Molecular Genetics, College Park, USA

参考文章(71)
Stephen D. Gillies, Immunocytokines: A Novel Approach to Cancer Immune Therapy Targeted Cancer Immune Therapy. pp. 241- 256 ,(2009) , 10.1007/978-1-4419-0170-5_14
S B Fleming, C A McCaughan, A E Andrews, A D Nash, A A Mercer, A homolog of interleukin-10 is encoded by the poxvirus orf virus. Journal of Virology. ,vol. 71, pp. 4857- 4861 ,(1997) , 10.1128/JVI.71.6.4857-4861.1997
Estelle Bettelli, Mercy Prabhu Das, Edward D Howard, Howard L Weiner, Raymond A Sobel, Vijay K Kuchroo, None, IL-10 Is Critical in the Regulation of Autoimmune Encephalomyelitis as Demonstrated by Studies of IL-10- and IL-4-Deficient and Transgenic Mice Journal of Immunology. ,vol. 161, pp. 3299- 3306 ,(1998)
Henry F. McFarland, Bruno Gran, Paul Conlon, Richard Houghten, Clemencia Pinilla, Bernhard Hemmer, Roland Martin, Marco Vergelli, Nick Ling, Cutting Edge: Predictable TCR Antigen Recognition Based on Peptide Scans Leads to the Identification of Agonist Ligands with No Sequence Homology Journal of Immunology. ,vol. 160, pp. 3631- 3636 ,(1998)
Eveline Trachsel, Frank Bootz, Michela Silacci, Manuela Kaspar, Hartwig Kosmehl, Dario Neri, Antibody-mediated delivery of IL-10 inhibits the progression of established collagen-induced arthritis Arthritis Research & Therapy. ,vol. 9, pp. 1- 9 ,(2007) , 10.1186/AR2115
Patrick A. Baeuerle, Torsten Dreier, Peter Kufer, Juergen M. Schanzer, A human cytokine/single-chain antibody fusion protein for simultaneous delivery of GM-CSF and IL-2 to Ep-CAM overexpressing tumor cells. Cancer Immunity Archive. ,vol. 6, pp. 4- ,(2006)
Brad Pohlman, John Sweetenham, Roger M Macklis, Review of clinical radioimmunotherapy. Expert Review of Anticancer Therapy. ,vol. 6, pp. 445- 461 ,(2006) , 10.1586/14737140.6.3.445
J. O. Lindsay, H. J. F. Hodgson, The immunoregulatory cytokine interleukin-10-a therapy for Crohn’s disease? Alimentary Pharmacology & Therapeutics. ,vol. 15, pp. 1709- 1716 ,(2001) , 10.1046/J.1365-2036.2001.01093.X
Sung-il Yoon, Brandi C. Jones, Naomi J. Logsdon, Bethany D. Harris, Ashlesha Deshpande, Svetlana Radaeva, Brian A. Halloran, Bin Gao, Mark R. Walter, Structure and Mechanism of Receptor Sharing by the IL-10R2 Common Chain Structure. ,vol. 18, pp. 638- 648 ,(2010) , 10.1016/J.STR.2010.02.009