Immunocytokines: A Novel Approach to Cancer Immune Therapy

摘要: The induction of a long-lived immune response to cancer has been long-term goal modern medicine, but date not realized despite evidence that the system is capable responding tumors. Immunocytokines represent new class biopharmaceuticals composed two well-known components – antibodies and cytokines with unique ability target tumor microenvironment thereby induce protective responses in preclinical mouse models. Several immunocytokines have now reached clinical development where it hoped exciting efficacy results will translate effective therapy for patients. Integration such treatment modality current standard care, as well newly emerging targeted therapies, be essential success this approach.