Method of preventing cancer recurrence

作者: Daniela Santoli , Giovanni Rovera , Alessandra Cesano

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摘要: Methods for treating cancer in a mammalian patient having and functional immune system, preventing recurrences of following completion therapy, are described. The methods involve administration course therapy with modified TALL-104 cells, without requiring the co-administration an immunosuppressive agent.

参考文章(60)
Daniela Santoli, Giovanni Rovera, Alessandra Cesano, Cytotoxic T-ALL cell lines and uses therefor ,(1992)
Hoxie Ja, Nowell Pc, Lange B, Bishop J, Cesano A, Santoli D, The severe combined immunodeficient (SCID) mouse as a model for human myeloid leukemias. Oncogene. ,vol. 7, pp. 827- 836 ,(1992)
N Heerema, S C Raimondi, P C Nowell, D Santoli, P E Steinherz, R O'Connor, B J Lange, J Minowada, E B Arenson, Pediatric leukemia/lymphoma with t(8;14)(q24;q11). Leukemia. ,vol. 6, pp. 613- 618 ,(1992)
A Cesano, R O'Connor, PC Nowell, B Lange, SC Clark, D Santoli, Establishment of a karyotypically normal cytotoxic leukemic T-cell line from a T-ALL sample engrafted in SCID mice Blood. ,vol. 81, pp. 2714- 2722 ,(1993) , 10.1182/BLOOD.V81.10.2714.2714
ROSEMARY O'Connor, ALESSANDRA Cesano, BRENT L Kreider, BEVERLY Lange, STEVEN C Clark, PETER C Nowell, JANET Finan, GIOVANNI Rovera, DANIELA Santoli, Growth factor-dependent differentiation along the myeloid and lymphoid lineages in an immature acute T lymphocytic leukemia. Journal of Immunology. ,vol. 145, pp. 3779- 3787 ,(1990)
D Santoli, S Visonneau, S C Clark, A Cesano, Cellular and molecular mechanisms of activation of MHC nonrestricted cytotoxic cells by IL-12. Journal of Immunology. ,vol. 151, pp. 2943- 2957 ,(1993)
Yoshimi Kawade, Haruhiko Kikuchi, Junkoh Yamashita, Youli Zu, Yuziro Namba, Masao Hanaoka, Shinichi Miyatake, Yoshihiko Watanabe, Kiyoshi Nishihara, Tsuneaki Sakata, Augmentation of Tumor Targeting in a Line of Glioma-specific Mouse Cytotoxic T-Lymphocytes by Retroviral Expression of Mouse γ-Interferon Complementary DNA Cancer Research. ,vol. 48, pp. 4730- 4735 ,(1988)
D Santoli, R O'Connor, G Rovera, S C Clark, A Cesano, P Phillips, B Lange, T L Colt, Synergistic and antagonistic effects of IL-1 alpha and IL-4, respectively, on the IL-2-dependent growth of a T cell receptor-gamma delta+ human T leukemia cell line. Journal of Immunology. ,vol. 144, pp. 4703- 4711 ,(1990)