Expansions of key protein families in the German cockroach highlight the molecular basis of its remarkable success as a global indoor pest.

摘要: The German cockroach, Blattella germanica, is a worldwide pest that infests buildings, including homes, restaurants, and hospitals, often living in unsanitary conditions. As disease vector producer of allergens, this species has major health economic impacts on humans. Factors contributing to the success cockroach include its resistance broad range insecticides, immunity many pathogens, ability, as an extreme generalist omnivore, survive most food sources. recently published genome shows B. germanica exceptionally high number protein coding genes. In study, we investigate functions 93 significantly expanded gene families with aim better understand despite such inhospitable We find expansions related detoxification insecticides allelochemicals, defense against digestion, sensory perception, regulation. These might have allowed develop multiple mechanisms enabled broad, flexible diet, thus explaining conditions under recurrent chemical control. findings resources presented here provide insights for understanding molecular will facilitate more effective