Emerging roles of non-coding RNAs in retinal diseases: A review.

作者: Lan‐Fang Sun , Xue‐Jiao Chen , Zi‐Bing Jin

DOI: 10.1111/CEO.13806

关键词:

摘要: Non-coding RNAs (ncRNAs) are key players in variety of biogenesis and biological functions. Their aberrant expression has been implicated disease progression. NcRNAs can be divided into short ncRNAs whose subtypes mainly microRNA (miRNA), long non-coding RNA (lncRNA) circular (circRNA). They involved cellular processes, including gene regulation, development disease. The retina is a remarkably sophisticated instrument with interconnected cell types the primary target many genetic diseases. In addition, terms retinal dyshomeostasis inflammation, seems to play critical roles Here, we provide an overview developing retina. We also review how does these function various diseases animal human models. These data indicate that regulate processes proliferation, differentiation, apoptosis contribute initiation progression

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