Impaired medullary circulation in postischemic acute renal failure.

摘要: Acute renal failure was induced in heparinized rats by clamping the artery for 45 min. Ten minutes after recirculation intrarenal blood flow distribution measured. For this purpose labelled microspheres were injected together with 86-Rb chloride. The used determination of cardiac output, total and cortical flow, calculations medullary flow. Total reduced from 7.6 to 3.8 ml . min-1 g-1 11.7 7.0 g-1. In outer stripe medulla there a reduction 2.5 1.4 inner more pronounced 1.8 0.2 zone 0.8 0.1 marked is suggestive ischemia, which might be responsible characteristic dysfunctions acute failure.