ISOLATION OF NORMAL T CELLS IN CHRONIC LYMPHATIC LEUKÆMIA

作者: Joseph Wybran , Shireen Chantler , H. Hugh Fudenberg

DOI: 10.1016/S0140-6736(73)90196-7

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摘要: Abstract Lymphocytes from patients with chronic lymphatic leukaemia (C.L.L.) show a poor response to mitogens. these and healthy were separated into two populations. One population, very rich in T cells, showed the same type of for both controls patients. In contrast, population cells derived C.L.L. lymphocytes did not respond at all Recombination experiments indicate that can be restored by addition cells. These findings demonstrate presence normally reactive T-cell It seems lack responsiveness is due dilution responding

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