Bidimensional Measurements in Brain Tumors: Assessment of Interobserver Variability

摘要: OBJECTIVE. Bidimensional tumor measurements indicating a greater than 25% increase in size are generally accepted as progression. We hypothesized that use of digital images and homogeneous reader population would have lower interobserver variability previous studies.SUBJECTS AND METHODS. Eight board-certified radiologists measured diameters three planes two consecutive MRI examinations 22 patients with contrast-enhancing high-grade brain tumors. Products were calculated, determinations made about progression (> area). A variance components model was run on diameter products the ratios maximal products. The included patient examination effect, residual effect.RESULTS. Complete agreement found among readers 10 cases (45%), all stable disease. In other 12 cases, at least one considered progressive disease present. ...