Bis (thiosemicarbazonato) Cu-64 Complexes for Positron Emission Tomography Imaging of Alzheimer's Disease
作者： Michelle T. Fodero-Tavoletti , Victor L. Villemagne , Brett M. Paterson , Anthony R. White , Qiao-Xin Li
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摘要: A bis (thiosemicarbazonato) complex radiolabeled with positron emitting Cu-64 can be used for a new and alternative method the non-invasive diagnosis of Alzheimer's disease using emission tomography (PET). Most imaging agents being investigated target amyloid-β plaque burden but our approach highlights altered copper homeostasis. This has potential to offer complementary information other diagnostic procedures that elucidate burden.
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