Action of lead(II) and aluminium (III) ions on iron-stimulated lipid peroxidation in liposomes, erythrocytes and rat liver microsomal fractions.
作者： Gregory J. Quinlan , Barry Halliwell , Christopher P. Moorhouse , John M.C. Gutteridge
DOI: 10.1016/0005-2760(88)90159-2
关键词:
摘要: Lead (Pb2+) ions accelerate the lipid peroxidation observed when Fe2+ are added to phospholipid liposomes at pH 5.5 or 7.4, although Pb2+ alone do not induce any peroxidation. Similarly, aluminium (Al3+) increase Fe2+-dependent liposomal 5.5. Both and Al3+ of erythrocytes induced by high concentrations H2O2 in presence azide, they also that occurs Fe2+-ADP is rat liver microsomes 7.4. It proposed increased may contribute toxic actions humans.
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