Expression of costimulatory molecule CD80 in colonic dysplasia in ulcerative colitis: an immunosurveillance mechanism against colorectal cancer?
作者： Marco Scarpa , Roubik Behboo , Imerio Angriman , Attilio Cecchetto , Renata D’Incà
DOI: 10.1007/S00384-006-0095-8
关键词:
摘要: Background and aims Ulcerative colitis is an established risk factor for colorectal cancer but dysplasia reports are much more frequent than invasive neoplasm diagnosis. The effective activation of T lymphocytes that provide antitumor surveillance requires the presence costimulation molecules such as CD80 CD86 on surface antigen-presenting cells. aim our study was to verify in vivo immunosurveillance mechanism early stages colon tumorigenesis.
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