Protocol for a collaborative meta-analysis of 5-HTTLPR, stress, and depression

作者: Robert C Culverhouse , Lucy Bowes , Naomi Breslau , John I Nurnberger Jr , Margit Burmeister

DOI: 10.1186/1471-244X-13-304

关键词:

摘要: Background Debate is ongoing about what role, if any, variation in the serotonin transporter linked polymorphic region (5-HTTLPR) plays depression. Some studies report an interaction between 5-HTTLPR and stressful life events affecting risk for depression, others a main effect of on while find no evidence either or effect. Meta-analyses multiple have also reached differing conclusions.

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