Cryosurgery treatment of actinic keratoses monitored by optical coherence tomography: a pilot study.

作者: Lotte Themstrup , Christina Banzhaf , Mette Mogensen , Gregor B.E. Jemec

DOI: 10.1159/000343770

关键词:

摘要: Background: Optical coherence tomography (OCT) is a non-invasive optical imaging technique providing high-resolution images. OCT may be useful as monitoring tool during treatment of actinic keratoses (AK) and skin cancer. Objective: To examine describe how morphology changes when the tissue exposed to effects cryotherapy. Methods: Normal ex vivo in AK lesions were examined. Cryotherapy was applied images acquired at defined time points. described. Results: produced an opaque iceball, freezing depth could not monitored by OCT. Vesicle formation after cryotherapy identified In no vesicle occurred. Conclusion: cannot monitor depth, but able visualise shortly Results add assumption that used treatments.

参考文章(21)
Sibel Zehra Aydin, Zoe Ash, Francesco Del Galdo, Helena Marzo-Ortega, Richard J. Wakefield, Paul Emery, Dennis McGonagle, Optical coherence tomography: a new tool to assess nail disease in psoriasis? Dermatology. ,vol. 222, pp. 311- 313 ,(2011) , 10.1159/000329434
Christine J. Ko, Actinic keratosis: Facts and controversies Clinics in Dermatology. ,vol. 28, pp. 249- 253 ,(2010) , 10.1016/J.CLINDERMATOL.2009.06.009
Leonard H. Goldberg, Baruch Kaplan, Irene Vergilis-Kalner, Jennifer Landau, Liquid nitrogen: temperature control in the treatment of actinic keratosis. Dermatologic Surgery. ,vol. 36, pp. 1956- 1961 ,(2010) , 10.1111/J.1524-4725.2010.01804.X
M Freeman, C Vinciullo, D Francis, L Spelman, R Nguyen, P Fergin, K‐E Thai, D Murrell, W Weightman, C Anderson, C Reid, A Watson, P Foley, A comparison of photodynamic therapy using topical methyl aminolevulinate (Metvix) with single cycle cryotherapy in patients with actinic keratosis: a prospective, randomized study. Journal of Dermatological Treatment. ,vol. 14, pp. 99- 106 ,(2003) , 10.1080/09546630310012118
Julia Welzel, Optical coherence tomography in dermatology: a review Skin Research and Technology. ,vol. 7, pp. 1- 9 ,(2001) , 10.1034/J.1600-0846.2001.007001001.X
METTE MOGENSEN, THOMAS MARTINI JOERGENSEN, BIRGIT MEINCKE NÜRNBERG, HANAN AHMAD MORSY, JAKOB B. THOMSEN, LARS THRANE, GREGOR B. E. JEMEC, Assessment of optical coherence tomography imaging in the diagnosis of non-melanoma skin cancer and benign lesions versus normal skin: observer-blinded evaluation by dermatologists and pathologists. Dermatologic Surgery. ,vol. 35, pp. 965- 972 ,(2009) , 10.1111/J.1524-4725.2009.01164.X
Keng-Ee Thai, Peter Fergin, Michael Freeman, Carl Vinciullo, David Francis, Lynda Spelman, Dedee Murrell, Chris Anderson, Warren Weightman, Catherine Reid, Alan Watson, Peter Foley, A prospective study of the use of cryosurgery for the treatment of actinic keratoses International Journal of Dermatology. ,vol. 43, pp. 687- 692 ,(2004) , 10.1111/J.1365-4632.2004.02056.X
Torsten Hinz, Lin-Kristin Ehler, Harald Voth, Ines Fortmeier, Tobias Hoeller, Thorsten Hornung, Monika-Hildegard Schmid-Wendtner, Assessment of tumor thickness in melanocytic skin lesions: comparison of optical coherence tomography, 20-MHz ultrasound and histopathology. Dermatology. ,vol. 223, pp. 161- 168 ,(2011) , 10.1159/000332845
Verena Ahlgrimm-Siess, Michael Horn, Silvia Koller, Ralf Ludwig, Armin Gerger, Rainer Hofmann-Wellenhof, Monitoring efficacy of cryotherapy for superficial basal cell carcinomas with in vivo reflectance confocal microscopy : A preliminary study Journal of Dermatological Science. ,vol. 53, pp. 60- 64 ,(2009) , 10.1016/J.JDERMSCI.2008.08.005
Vrushali R. Korde, Garret T. Bonnema, Wei Xu, Chetankumar Krishnamurthy, James Ranger-Moore, Kathylynn Saboda, Lisa D. Slayton, Stuart J. Salasche, James A. Warneke, David S. Alberts, Jennifer K. Barton, Using optical coherence tomography to evaluate skin sun damage and precancer. Lasers in Surgery and Medicine. ,vol. 39, pp. 687- 695 ,(2007) , 10.1002/LSM.20573