摘要: Development of new medicines for malaria is a challenging and important topic applied research because malarial parasites rapidly adapt to man-made interventions. Best studied examples are widely used drugs such as chloroquine, sulfadoxin-pyrimethamine (SP), and, recently, artemisinins; all them can lose efficacy after large-scale introduction. In addition drugs, vaccines re-emerged on the agenda funding bodies institutions period quietness desperation. This time communities' aims high: registered effective malaria-vaccine. So far, only one candidate shows modest [1], quantum leap in vaccine research, whereas others have not met high expectations [2–4]. this overview, I will summarize basic thoughts principles behind our work illustrate with current projects my group.
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