Mitochondria as therapeutic targets for cancer chemotherapy

作者: L Galluzzi , N Larochette , N Zamzami , G Kroemer

DOI: 10.1038/SJ.ONC.1209598

关键词:

摘要: … cancer-relevant regulation of MOMP and discuss the molecular mode of action of MOMP inducers and of agents that enhance the proapoptotic activity of mitochondrial death effectors. …

参考文章(237)
Robert A. Haworth, Douglas R.M Hunter, Control of the mitochondrial permeability transition pore by high-affinity ADP binding at the ADP/ATP translocase in permeabilized mitochondria. Journal of Bioenergetics and Biomembranes. ,vol. 32, pp. 91- 96 ,(2000) , 10.1023/A:1005568630151
D. Poncet, P. Boya, D. Métivier, N. Zamzami, G. Kroemer, Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization. Apoptosis. ,vol. 8, pp. 521- 530 ,(2003) , 10.1023/A:1025546525894
M. A. de Pablo, S. A. Susin, E. Jacotot, N. Larochette, P. Costantini, L. Ravagnan, N. Zamzami, G. Kroemer, Palmitate induces apoptosis via a direct effect on mitochondria. Apoptosis. ,vol. 4, pp. 81- 87 ,(1999) , 10.1023/A:1009694124241
Stéphane Oudard, Antoine Carpentier, Eugeniu Banu, François Fauchon, Denis Celerier, Marie F Poupon, Bernard Dutrillaux, Jean M Andrieu, Jean Y Delattre, Phase II study of lonidamine and diazepam in the treatment of recurrent glioblastoma multiforme. Journal of Neuro-oncology. ,vol. 63, pp. 81- 86 ,(2003) , 10.1023/A:1023756707900
Kazuhiro Takuma, Patamawan Phuagphong, Eibai Lee, Koichi Mori, Akemichi Baba, Toshio Matsuda, Anti-apoptotic effect of cGMP in cultured astrocytes: inhibition by cGMP-dependent protein kinase of mitochondrial permeable transition pore. Journal of Biological Chemistry. ,vol. 276, pp. 48093- 48099 ,(2001) , 10.1074/JBC.M108622200
Shie-Pon Tzung, Kristine M. Kim, Gorka Basañez, Chris D. Giedt, Julian Simon, Joshua Zimmerberg, Kam Y. J. Zhang, David M. Hockenbery, Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3. Nature Cell Biology. ,vol. 3, pp. 183- 191 ,(2001) , 10.1038/35055095
Yukitoshi Nagahara, Masahiko Ikekita, Takahisa Shinomiya, Immunosuppressant FTY720 induces apoptosis by direct induction of permeability transition and release of cytochrome c from mitochondria. Journal of Immunology. ,vol. 165, pp. 3250- 3259 ,(2000) , 10.4049/JIMMUNOL.165.6.3250
Cecília M. P. Rodrigues, Susana Solá, Rui Silva, Dora Brites, Bilirubin and Amyloid-β Peptide Induce Cytochrome c Release Through Mitochondrial Membrane Permeabilization Molecular Medicine. ,vol. 6, pp. 936- 946 ,(2000) , 10.1007/BF03401828