Synthesis and Anticancer Activity of a Novel Series of Tetrazolo[1,5- a ]quinoline Based 1,2,3-Triazole Derivatives
作者： R. Nagaraju , K. Gopichand , N. N. Rao , A. M. Ganai , E. Kishan
DOI: 10.1134/S1070363220020255
关键词:
摘要: We report here the synthesis of a novel series tetrazolo[1,5-a]quinoline based 1,2,3-triazoles from acetaniline via Vilsmeier–Haack reaction, Claisen–Schmidt condensation and 1,3-dipolar Click reaction. The newly synthesized compounds have been tested for their anticancer activity against panel three cell lines such as cervix (SiHa), brest (MDA-MB-231) pancreatic carcinoma (PANC-1). Most possess potent activity.
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