Systemic toxicity related to metal hip prostheses
作者： S. M. Bradberry , J. M. Wilkinson , R. E. Ferner
DOI: 10.3109/15563650.2014.944977
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摘要: AbstractIntroduction. One in eight of all total hip replacements requires revision within 10 years, 60% because wear-related complications. The bearing surfaces may be made cobalt/chromium, stainless steel, ceramic, or polyethylene. Friction between and corrosion non-moving parts can result increased local systemic metal concentrations. Objectives. To identify systematically review published reports toxicity attributed to released from implants propose criteria for the assessment these patients. Methods. Medline (from 1950) Embase 1980) were searched 28 February 2014 using search terms (text/abstract) chrom* cobalt* [toxic* intox* poison* adverse effect complication] [prosthes* ‘joint replacement’ arthroplast*] PubMed (all available years) was term ((“Chromium/adverse effects”[Mesh] OR “Chromium/poisoning”[Mesh] “Chromium/toxicity”[Mesh]) (“Cobalt/ad...
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