作者: Jane W. Marsh , Lee H. Harrison
DOI: 10.1016/B978-0-12-801214-7.00010-7
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摘要: Clostridium difficile is a spore-forming, toxin-producing human and animal pathogen. In humans, disease primarily hospital-associated; antibiotic exposure advanced age are major risk factors. However, the epidemiology of C. has changed recently with emergence an antibiotic-resistant lineage community-associated cases among individuals without traditional The finding in food animals retail foods raised concerns that may be foodborne role as cause infection (CDI) been difficult to assess. Transient asymptomatic carriage healthy subjects reported but source colonization unclear. Prospective studies investigating associations diet, carriage, CDI required understand complex difficile. On-farm management molecular epidemiologic surveillance will necessary mitigate emergence, spread, potential zoonotic transmission this important