The epithelial cadherin -160C/A polymorphism is associated with decreased risk of colorectal cancer: a case-control study.
作者： Wenhuan Li , Deshuang Xiao , Huawen Wu , Lewei Xu
DOI: 10.1007/S10238-019-00586-3
关键词:
摘要: The epithelial cadherin (CDH1) is an important determinant of tumor progression. Previous studies have indicated that the CDH1 -160C/A polymorphism was associated with risk colorectal cancer (CRC). However, they yielded conflicting results. Thus, we conducted this case-control study to evaluate association between and susceptibility CRC in a Chinese population. We recruited 351 cases 411 controls study. genotype performed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOFMS). This found decreased Han Subgroup analyses showed among males non-drinkers. In addition, significantly observed patients size ≤ 5 cm, AA protective role no lymph node metastasis. conclusion, shows
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