Intracoronary Fibrinolytic Therapy in Acute Myocardial Infarction

摘要: Abstract We performed a randomized trial comparing intracoronary administration of streptokinase versus dextrose placebo within six hours after the onset symptoms acute myocardial infarction in 40 patients. The base-line clinical, hemodynamic, and angiographic findings were similar control streptokinase-treated groups. Reestablishment flow occurred 12 20 patients treated with 2 given (P<0.05). Left ventricular function, ejection fraction, regional wall motion, measured before immediately intervention, serial radionuclide fractions, at treatment, days, 5 months, compared according to type treatment (streptokinase vs. placebo) outcome therapy (reperfusion no reperfusion). No statistically significant differences between groups found. Thus, although was more effective than achieving reperfusion, we detected improvement left ventricul...