Selective chemical disconnection of the uriniferous tubes of the first order in rabbits
作者： J. M�hes , L. Decsi , F. Varga , S. Kov�cs
DOI: 10.1007/BF00259716
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摘要: Aristolochiasaure ruft bei den Kaninchen eine selektive Nekrose der Epithelzellen in proximalen gewundenen Nierenkanalchen und Nierenrindenischamie hervor, wahrend sie die anderen Teile des Kanalchensystems Glomeruli intakt last. Untersuchungen uber Nierentatigkeit solcher Tiere ergaben, das p-Aminohippursaure- Phenolrotausscheidung nach isolierter Zerstorung Kanalchen I. Ordnung vollig eingestellt wird. Die konnen nur 80% filtrierten Wassers zuruckresorbieren. Wirkung exogenen antidiuretischen Hormons wird aufgehoben. alkalische Phosphataseaktivitat, sowie Bernsteinsauredehydrogenaseaktivitat nehmen stark ab, saure Phosphataseaktivitat sich nicht verandert. tubulare Zuckerresorptionsfahigkeit ist erhalten.
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