Characterization of SeseC_01411 as a surface protective antigen of Streptococcus equi ssp. zooepidemicus.
作者： Honglin Xie , Zigong Wei , Chunquan Ma , Shun Li , Xiaohong Liu
DOI: 10.1016/J.RVSC.2018.05.007
关键词:
摘要: Streptococcus equi ssp. zooepidemicus (Streptococcus zooepidemicus, SEZ) is a commensal bacterium related to opportunistic infections of many species, including humans, dogs, cats, and pigs. SeseC_01411 has been proven be immunogenic. However, its protective efficacy remained evaluated. In the present study, purified recombinant could elicit strong humoral antibody response protect against lethal challenge with virulent SEZ in mice. Our finding confirmed that distributes on surface SEZ. addition, hyperimmune sera efficiently kill bacteria phagocytosis test. The study identified immunogenic protein, SeseC_01411, as novel antigen
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