Process for making human antibody producing B-lymphocytes

作者: Michael K. Hoffmann

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摘要: Antibody producing human B-lymphocytes are produced by a process which comprises culturing in tissue culture medium the presence of an antigen; helper signal agents comprising monocytes or monocyte conditioned containing Interleukin 1 (I1-1), and T-lymphocytes T-lymphocyte replacing factor; serum; thereafter recovering antibody cells from medium.

参考文章(1)
A. L. LUZZATI, H. HENGARTNER, M. H. SCHREIER, Induction of plaque-forming cells in cultured human lymphocytes by combined action of antigen and EB virus. Nature. ,vol. 269, pp. 419- 420 ,(1977) , 10.1038/269419A0