A randomised controlled trial of an automated oxygen delivery algorithm for preterm neonates receiving supplemental oxygen without mechanical ventilation

摘要: Aim Providing consistent levels of oxygen saturation (SpO2) for infants in neonatal intensive care units is not easy. This study explored how effectively the Auto-Mixer® algorithm automatically adjusted fraction inspired (FiO2) to maintain SpO2 within an intended range extremely low birth weight receiving supplemental without mechanical ventilation. Methods Twenty were randomly assigned group or manual intervention and studied 12 h. The target was 85–93%, outcomes percentage time target, variability, >95%, received interventions. Results The 58 ± 4% 33.7 ± 4.7% group, >95% 26.5% vs 54.8%, average FiO2 89.8% 92.2% 37% 44.1%, interventions 0 80 (p < 0.05). Brief periods SpO2 < 85% occurred more frequently group. Conclusion The increased that decreased with high spontaneously breathing oxygen.