A new tyrosine kinase inhibitor from the marine brown alga Stypopodium zonale.

摘要: From the lipophilic extract of marine brown alga Stypopodium zonale (Dictyotaceae) new terpenoid compound stypoquinonic acid (1) together with known compounds taondiol (2) and atomaric (3) were isolated. The structures all isolates determined from their spectroscopic data, including 1- 2-dimensional NMR methods. compound, 1, (3), showed inhibition tyrosine kinase (p56lck).