Racial differences in venous thromboembolism

摘要: The incidence of venous thrombosis (VTE) varies by race, with African-Americans having over 5-fold greater than Asian-ancestry populations, and an intermediate risk for European Hispanic populations. Known racial differences in genetic polymorphisms associated do not account this gradient risk, nor known variations environmental factors. Data on the factors VTE outside Europe North America non-European ancestry populations are sparse. Common European-Ancestry such as factor V Leiden prothrombin G20210A, factors, obesity, may some increased high VIII, von Willebrand low protein C levels prevalence obesity explain African-Americans. rates Asian be partially explained clinical suspicion a perceived low-risk population lack access to healthcare other As thrombosis, surgery treatment cancer, applicable more people, increases developing world, surveillance systems improve, increase previously While race due predisposition will probably always present, understanding reasons help providers develop strategies minimize all